Transition between B-DNA and Z-DNA: Free Energy Landscape for the B−Z Junction Propagation
نویسندگان
چکیده
منابع مشابه
Transition between B-DNA and Z-DNA: free energy landscape for the B-Z junction propagation.
Canonical, right-handed B-DNA can be transformed into noncanonical, left-handed Z-DNA in vitro at high salt concentrations or in vivo under physiological conditions. The molecular mechanism of this drastic conformational transition is still unknown despite numerous studies. Inspired by the crystal structure of a B-Z junction and the previous zipper model, we show here, with the aid of molecular...
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ژورنال
عنوان ژورنال: The Journal of Physical Chemistry B
سال: 2010
ISSN: 1520-6106,1520-5207
DOI: 10.1021/jp103419t